Prof. D. S. Rawat


Prof. D. S. Rawat

Professor Diwan S Rawat joined the Department as a Reader in July 2003, and was promoted to Professor in March 2010. He obtained his master’s degree from Kumaun University, Nainital in 1993 and was honoured with the merit certificate for securing first position in the University. He did his Ph.D. in Medicinal Chemistry from Central Drug Research Institute, Lucknow. He worked two years in a Pharmaceutical Industry and did postdoctoral work at Indiana University and Purdue University, USA. He was an Assistant Professor of Medicinal Chemistry at National Institute of Pharmaceutical Education and Research (NIPER), Mohali, before joining University of Delhi in 2003. Prof. Rawat has published over 148 research papers, authored a book, three book chapters, and nine patents to his credit. His work has been cited over 4660 times with h–index of 42. His research interests lies in the areas of development of small organic molecules as anticancer, antimalarial, antimicrobial and anti-Parkinson agents and nano-catalysis.

Prof. Rawat was a Sectional President of Indian Science Congress (2019-2020) and is a recipient of CRSI young scientist award (2007); ISCB young scientist award (2010); Prof. D. P. Chakraborty 60th Birth Anniversary Commemoration Award (2007); VC`s Pratik Chinha Samman, Kumaun University Nainital (2011); Gold Badge and Diploma, International Scientific Partnership Foundation, Russia (2015); Professor RC Shah Memorial Lecture Award, Indian Science Congress (2015); Professor SP Hiremath Memorial Award, Indian Council of Chemist (2016); and he is a Visiting Professor, Japan Advanced Institute of Science and Technology (JAIST), Japan. He is Fellow of Royal Society of Chemistry (FRSC) and CChem (London). Prof. Rawat has supervised twenty PhD students.

Prof. Rawat is an Associate Editor of Nature Scientific Reports and RSC Advances, International Journal of Drug Discovery and also serves on the Editorial Advisory Board of Anti-Cancer Agents in Medicinal Chemistry, and Marine Drugs. He served as a Guest Editor of Anti-Cancer Agents in Medicinal Chemistry and Current Protein and Peptide Science.

Selected publications (Last five years):

  1. Aparna Bahuguna, Diwan S. Rawat* Recent trends and strategies for the anti-tubercular drug development, Med. Res. Rev. 40, 263-292 (2020). Impact Factor: 9.791.
  2. Upasana Gulati, U. Chinna Rajesh, Diwan S. Rawat*, JM Zaleski, MgO@Ag hybrid nanocatalysts for activation of CO2 at ambient pressure to afford esters and lactones, Green Chem. (2020). Impact Factor: 9.405.
  3. Gunjan Purohit, Aneeta Kharkwal Diwan S. Rawat*, CuIn-ethylxanthate a “versatile precursor” for photosensitization of graphene-quantum dots and nanocatalyzed synthesis of imidazopyridines with ideal green chemistry metrics. ACS Sustainable Chem. Engg. (2020). Impact Factor: 6.94.
  4. Upasana Gulati, U. Chinna Rajesh, Diwan S. Rawat*, Renewable RGO@CuI nanocomposites for redox triggered single electron transfer (SET) reaction under aerobic and anaerobic conditions, ChemCatChem, (2020). Impact Factor: 4.495.
  5. Garima Arora, Gagandeep, Assirbad Behura, Tannu Priya Gosain, R. P. Shaliwal, Saqib Kidwai, Padam Singh, Shamseer Kulangara Kandi, Rohan Dhiman, Diwan S. Rawat and Ramandeep Singh, NSC 18725, a pyrazole derivative inhibits growth of intracellular Mycobacterium tuberculosis by induction of autophagy Front. Microbiol. 10, 3051 – 3063 (2020), Impact Factor: 4.259.
  6. Gagandeep, Prince Kumar, Shamseer Kulangara Kandi, Kasturi Mukhopadhyay, Diwan S. Rawat*, Synthesis of novel monocarbonyl curcuminoids, evaluation of their efficacy against MRSA, including ex vivo infection model and their mechanistic studies, Eur. J. Med. Chem. (2020). Impact Factor: 4.816.
  7. Upasana Gulati, U. Chinna Rajesh, Diwan S. Rawat*, Magnetically recoverable Ni@CuI hybrid nanocatalysts to afford spiropyrroline heterocycles from ketoximes and alkenes, Asian J. Org. Chem. (2020). Impact Factor: 3.275.
  8. Gunjan Purohit, Diwan S. Rawat*, Oliver Reiser, Palladium nanocatalysts encapsultated on porous silica@magnetic carbon-coated cobalt nanoparticles for sustainable hydrogenations of nitroarenes, alkenes and alkynes, ChemCatChem, 12, 569 – 575 (2020). Impact Factor: 4.495.
  9. Kamlesh Kumar, Prashant Kumar, Penny Joshi, Diwan S Rawat*, IBX-TfOH mediated oxidation of alcohols to aldehydes and ketones under mild reaction conditions, Tetrahedron Letters, (2020). Impact Factor: 2.379.
  10. Gunjan Purohit, Diwan S. Rawat*, Hierarchically porous mixed oxide sheet like copper-aluminium (CuAl-MO) nanocatalyzed synthesis of 2-alkynyl-pyrrolidines/piperidines and their ideal green chemistry metrics. ACS Sustainable Chem. Engg. 7, 19235−19245 (2019). Impact Factor: 6.94.
  11. Mohit Tripathi, Dale Taylor, Shabana I. Khan, Babu L. Tekwani, Prija Ponnan, Thirumurthy Velpandian, Ujjalkumar Das, Diwan S. Rawat* Hybridization of fluoro-amodiaquine (FAQ) with pyrimidines: Synthesis, in vitro and in vivo antimalarial potency of FAQ-pyrimidines, ACS Med. Chem. Lett. 10, 714719 (2019). Impact Factor: 3.84.
  12. Girjesh Kumar Verma, Manish Rawat, Diwan S. Rawat* [Cp*Co(CO)I2] Catalysed C―C bond formation and [2+2+2] annulation of 1,3-dicarbonyls to terminal alkynes, Eur. J. Org. Chem. 4101–4104 (2019). Impact Factor: 3.029.
  13. Manish Rawat, Diwan S Rawat, CuI@Al2O3 catalyzed synthesis of 2-aminonicotinonitriles derivatives under solvent free condition, Tetrahedron Lett. 60, 1153 – 1157 (2019), [Highlighted in the Cover Page], Impact Factor: 2.379.
  14. S. S. Maurya, A. Bahuguna, S. I. Khan, D. Kumar, R. Kholiya, Diwan S. Rawat*, N-Substituted aminoquinoline-pyrimidine hybrids:  Synthesis, in vitro antimalarial activity evaluation and docking studies. Eur. J. Med. Chem. 162, 277 – 289  (2019), Impact Factor: 4.816.
  15. Prince Kumar, S. K. Kandi, S. Manohar, K. Mukhopadhyay, Diwan S. Rawat*, Monocarbonyl curcuminoids with improved stability as antibacterial agents against Staphylococcus aureus and their mechanistic studies, ACS Omega, 4, 675 – 687 (2019), Impact Factor: 2.584.
  16. B. Negi, P. Poonan, M. F. Ansari, D. Kumar, S. Aggarwal, R. Singh, A. Azam, Diwan S Rawat* Synthesis, antiamoebic activity and docking studies of metronidazole-triazole-styryl hybrids. Eur. J. Med. Chem. 150, 633 – 641 (2018). Impact Factor: 4.816.
  17. B. Negi, Diwan S Rawat* Antituberculosis activity evaluation of thymol Schiff bases, Chem. Biol. Interface. 8, 244-254 (2018).
  18.  Beena Negi, Diwan S Rawat* Synthesis, Characterization, and Antimycobacterial Activity of Novel Thymol-Triazole Hybrids, Ind. J. Het. Chem. 28, 113-124 (2018).
  19. Upasana Gulati, U. Chinna Rajesh, and Diwan S. Rawat* RGO@CuO Nanocomposites From A Renewable Copper Mineral Precursor: A Green Approach For Decarboxylative C(sp3)-H Activation Of Proline Amino Acid To Afford Value-Added Synthons. ACS Sustainable Chem. Eng. 6, 10039−10051 (2018). Impact Factor: 6.94.
  20. Manish Rawat and Diwan S. Rawat* Copper oxide nanoparticle catalysed synthesis of imidazo[1,2-a]pyrimidine derivatives, their optical properties and selective fluorescent sensor towards zinc ions. Tetrahedron Lett. 59, 2341 – 2346 (2018). [Highlighted in the Cover Page], Impact Factor: 2.379. [Highlighted by Synfacts 2018; 14(08): 0883].
  21. G. Purohit, U. Chinna Rajesh, Diwan S. Rawat*, Hierarchically porous sphere-like copper oxide (HS-CuO) nanocatalyzed synthesis of benzofuran isomers with anomalous selectivity and their ideal green chemistry metrics. ACS Sustainable Chem. Eng. 5, 6466 – 6477 (2017). Impact Factor: 6.97.
  22. Mohit Tripathi, Shabana I. Khan, Prija Ponnan, Rohit Kholiya, Diwan S. Rawat*,  Aminoquinoline-pyrimidine-modified anilines: Synthesis, in vitro antiplasmodial activity, cytotoxicity, mechanistic studies and ADME predictions, ChemSelect, 2, 9074 – 9084 (2017). Impact Factor: 1.505.
  23. U. Gulati, U. Chinna Rajesh, N. Bunekar, Diwan S. Rawat* Decarboxylative coupling strategy to afford N-heterocycles driven by silica nanosphere embedded copper oxide (Cu@SiO2-NS). ACS Sustainable Chem. Eng. 5, 4672 – 4682 (2017). Impact Factor: 6.97.
  24. P. Linga Reddy, Mohit Tripathi,  R. Arundhathi, Diwan S. Rawat*,   Chemoselective hydrazine-mediated transfer hydrogenation of nitroarenes by Co3O4 nanoparticles immobilized on a Al/Si-mixed oxide support, Chemistry - An Asian Journal, 12, 785 – 791 (2017). Impact Factor: 4.592. [Highlighted by Synfacts 2017; 13(07): 0766].
  25. U. Gulati, S. Rawat, U. Chinna Rajesh, Diwan S. Rawat* CuO@Fe2O3 catalyzed C1-alkynylation of tetrahydroisoquinolines (THIQs) via A3 coupling and its decarboxylative strategies, New J. Chem. 41, 8341-8346 (2017). Impact Factor: 3.269.
  26. Archana Gupta, Rohit Kholiya, Diwan S. Rawat,* Lewis acid mediated tetrahydrofuran synthesis via [3+2] cycloaddition reaction of 2-arylcyclopropyl ketones with aldehydes, Asian J. Org. Chem. 6, 993 – 997 (2017). Impact Factor: 3.275.
  27. P. Linga Reddy, R. Arundhathi, Mohit Tripathi, Prashant Chauhan, Ning Yan, Diwan S. Rawat* Solvent free oxidative synthesis of 2-substituted benzimidazoles by immobilized cobalt oxide nanoparticles on alumina/silica support, ChemSelect, 2, 3889 – 3895 (2017). Impact Factor: 1.505.
  28. P. Linga Reddy, Shabana I. Khan, Prija Ponnan, Mohit Tripathi, Diwan S. Rawat* Design, synthesis and evaluation of 4-aminoquinoline-purine hybrids as potential antiplasmodial agents; Eur. J. Med. Chem. 126, 675-686 (2017). Impact Factor: 4.816.
  29. Beena Negi, Deepak Kumar, Diwan S. Rawat*, Marine peptides as anticancer agents: A remedy to mankind by nature, Curr. Protein Pept. Sci. 18, 885-904 (2017). Impact Factor: 3.154.
  30. Rohit Kholiya, Shabana I. Khan, Aparna Bahuguna, Mohit Tripathi, Diwan S. Rawat* N-Piperonyl substitution on aminoquinoline-pyrimidine hybrids:  Effect on the antiplasmodial potency; Eur. J. Med. Chem. 131, 126 – 140 (2017). Impact Factor: 4.816.
  31. Shiv Shyam Maurya, Shabana I. Khan, Deepak Kumar, Aparna Bahuguna, Diwan S. Rawat* Synthesis, antimalarial activity, heme binding and docking studies of N-substituted 4-aminoquinoline-pyrimidine molecular hybrids; Eur. J. Med. Chem. 129, 175 – 185 (2017). Impact Factor: 4.816.
  32. U. Chinna Rajesh, Upasana Gulati and Diwan S. Rawat* Cu(II)-Hydromagnesite catalyzed synthesis of tetrasubstituted propargylamines and pyrrolo[1,2-a]quinolines via KA2, A3 couplings and their decarboxylative versions, ACS Sustainable Chem. Eng. 4, 3409 – 3419 (2016). Impact Factor: 6.97.
  33. Upasana Gulati, U. Chinna Rajesh and Diwan S. Rawat*, CuO/Fe2O3 NPs: Robust and magnetically recoverable nanocatalyst for decarboxylative A3 and KA2 coupling reactions under neat conditions, Tetrahedron Letters, 57, 4468 – 4472 (2016) [Highlighted in the Cover Page] [Synfacts 2016, 12(12), 1314]. Impact Factor: 2.379.
  34. P. Linga Reddy, R. Arundhathi, Mohit Tripathi and Diwan S. Rawat* CuI nanoparticles mediated expeditious synthesis of 2-substituted benzimidazoles using molecular oxygen as oxidant, RSC Adv, 6, 53596 - 53601 (2016). Impact Factor: 2.936.
  35. U. Chinna Rajesh, V. Satya Pavan, Diwan S. Rawat*, Copper supported hematite NPs as magnetically recoverable nanocatalysts for one-pot synthesis of aminioindolizines and pyrrolo[1,2-a]quinolines, RSC Adv, 6, 2935 – 2943 (2016). Impact Factor: 2.936. Highlighted in SYNFACTS 2016, 12(4), 0427.
  36. Beena Negi,  Deepak Kumar,  Widuranga Kumbukgolla, Sampath Jayaweera, Prija Ponnan, Ramandeep Singh, Sakshi Agarwal, Diwan S. Rawat*, Anti-methicillin resistant Staphylococcus aureus activity, synergism with oxacillin and molecular docking studies of metronidazole-triazole hybrids, Eur. J. Med. Chem. 115, 426 – 437 (2016). Impact Factor: 4.816.
  37. Amit Anthwal, Kundan Singh, M.S.M. Rawat, Amit K. Tyagi, Ashanul Haque, Imran Ali, Diwan S. Rawat* Synthesis of 4-piperidone based curcuminoids with anti-inflammatory and anti-proliferation potential in human cancer cell lines, Anti Cancer Agents Med Chem, 16, 841-851 (2016). Impact Factor: 3.14.
  38. U. Chinna Rajesh, V. Satya Pavan, Diwan S. Rawat*, Hydromagnesite rectangular thin sheets as efficient heterogeneous catalysts for the synthesis of novel 3-substituted indoles via Yonemitsu-type condensation in water, ACS Sustainable Chem. Eng. 3, 1536 – 1543 (2015). Impact Factor: 6.97.
  39. P. Linga Reddy, R. Arundhathi,  Diwan S. Rawat* Cu(0)@Al2O3/SiO2 NPs: Efficient reusable catalyst for the cross coupling reactions of aryl chlorides with amines and anilines, RSC Adv, 5, 92121-92127 (2015). Impact Factor: 2.936. Highlighted in SYNFACTS 2016, 12(2), 0214.
  40. Seema Joshi,   Rikeshwer Prasad Dewangan,  Mohammad Shahar Yar,   Diwan S.Rawat,  Santosh Pasha, N-Terminal aromatic tag induced self assembly of tryptophan-arginine rich ultra short sequences and their potent antibacterial activity, RSC Adv, 5, 68610 – 68620 (2015), Impact Factor: 2.936.
  41. Anuj Thakur, P. Linga Reddy, Mohit Tripathi, Diwan S. Rawat*, Facile construction of 3-indolochromenes and 3-indoloxanthenes via EDDF catalyzed one-pot three component reactions. New J. Chem. 39, 6253 – 6260 (2015). Impact Factor: 3.277.
  42. U. Chinna Rajesh, Gunjan Purohit, Diwan S. Rawat* Facile one-pot synthesis of N-heterocycles using CuI/CSP composites as efficient recyclable nanocatalysts with anomalous selectivity under green conditions, ACS Sustainable Chem. Eng. 3, 2397 – 2404  (2015). Impact Factor: 6.97.
  43. Deepak Kumar, Beena Negi, Diwan S. Rawat* The current anti-TB agents and the challenges ahead. Fut. Med. Chem. 7, 1981 – 2003 (2015), Invited article. Impact Factor: 4.01.
  44. Sunny Manohar, V. Satya Pavan, Dale Taylor, Deepak Kumar, Prija Ponnan, Lubbe Wiesner, Diwan S. Rawat*, Highly active 4-aminoquinoline-pyrimidine based molecular hybrids as potential next generation antimalarial agents, RSC Adv 5, 28171 – 28186 (2015) Impact Factor: 2.936.
  45. Penny Joshi, Diwan S. Rawat*, Synthesis and characterization of theophylline-triazole and theophylline-triazole-coumarin based molecular hybrids, Ind. J. Het. Chem. 24, 411 – 418 (2015). Invited article.
  46. Sunny Manohar, Anuj Thakur, Rohit Bhatia, Suresh Walia, Prija Ponnan, Diwan S. Rawat,* Antibacterial and antioxidant activity evaluation of novel symmetrical and unsymmetrical C5-curcuminoids, Ind J. Chem Sec B, 54B, 1235 – 1246 (2015).
  47. Mohit Tripathi, Shabana I. Khan, Anuj Thakur, Prija Ponnan, Diwan S. Rawat*, 4-Aminoquinoline-pyrimidine-aminoalkanols: Synthesis, in vitro antimalarial activity, docking studies and ADME predictions, New J. Chem. 39, 3474 – 4383 (2015). Impact Factor: 3.277.
  48. U. Chinna Rajesh, Rohit Kholiya, Anuj Thakur, Diwan S. Rawat*, [TBA][Gly] ionic liquid promoted multi-component synthesis of 3-substituted indoles and indolyl-4H-chromenes” Tetrahedron Lett. 56, 1790 - 1793  (2015) [100th PAPER]. Impact Factor: 2.379.
  49. Deepak Kumar, Garima Khare, Beena, Saqib Kidwai, Anil K. Tyagi, Ramandeep Singh, Diwan S. Rawat*, Novel isoniazid-amidoether derivatives: Synthesis, characterization and antimycobacterial activity evaluation, Med. Chem. Commun. 6, 131 - 137 (2015). Impact Factor: 2.722.
  50. U. Chinna Rajesh, Jinfeng Wang, Stuart Prescott,  Takuya Tsuzuki, Diwan S. Rawat*, RGO/ZnO nanocomposite: An efficient sustainable heterogeneous amphiphilic catalyst for the synthesis of 3-substituted indoles in water. ACS Sustainable Chem. Eng. 3, 9 – 18 (2015) [Highlighted in the Cover Page]. Impact Factor: 6.97.
  51. Shamseer K. Kandi, Sunny Manohar, Christian E. Vélez Gerena, Beatriz Zayas, Sanjay V. Malhotra, Diwan S. Rawat*; C5-curcuminoid-4-aminoquinoline based molecular hybrids: Design, synthesis and mechanistic investigation of anticancer activity, New J. Chem. 39, 224 - 234 (2015). Impact Factor: 3.277.
  52. Deepak Kumar, Shabana I. Khan, Prija Poonan, Diwan S. Rawat* “4-Aminoquinoline-pyrimidine hybrids: Synthesis, antimalarial activity, heme binding and docking studies” Eur. J. Med Chem. 89, 490 - 502 (2015). Impact Factor: 4.816.
  53. K. Kranthi Raj, Sunny Manohar, Venkateswara Rao Talluri, Diwan S. Rawat* Insights into activity enhancement of 4-aminoquinoline based hybrids using atom-based and field-based QSAR Studies, Med. Chem. Res. 24, 1136- 1154 (2015). Impact Factor: 1.621.
  54. Rini Joshi, Vishwajeet Rohil, Shvetambri Arora, Diwan S. Rawat, H. G. Raj et al, The competence of 7, 8-diacetoxy-4-methylcoumarin and other polyphenolic acetates in mitigating the oxidative stress and their role in angiogenesis, Curr. Topics Med. Chem. 15, 179 – 186 (2015). Impact Factor: 3.632.


  1. Diwan S Rawat*, Binghe Wang, Nitin Kumar, Sunny Manohar, Xiaochuan Yang, Guojing Sun, Curcumin analogues and methods of making and using thereof. Patent No: US 9884825B2 (February 6, 2018),
  2. Diwan S Rawat*, Sunny Manohar, Ummadisetty Chinna Rajesh, Deepak Kumar, Anuj Thakur, Mohit Tripathi, Panyala Linga Reddy, Shamseer Kulangara Kandi, Satyapavan Vardhineni, Kwang-Soo, and Chun-Hyung Kim, Amino-quinoline based hybrids and uses thereof. Pub no: US 2017/0209441 A1; WO2013134047 A3, PCT/US2013/028329 (2013); EP Application No. 13758678, filed 10/7/2014; PCT/US2013/28329, filed 2/28/2013.
  3. Diwan S Rawat*, Sunny Manohar, U. Chinna Rajesh, Amino-quinoline based hybrids and uses thereof, IN 283657 (2017). 
  4. Diwan S Rawat*, Binghe Wang, Nitin Kumar, Sunny Manohar, Xiaochuan Yang, Guojing Sun, Curcumin analogues and methods of making and using thereof. PCT/US2013/053216 (2014).
  5. Diwan S. Rawat,* Mukul Sharma, Nilanjan Roy, Rajesh K. Rohilla, Preparation of Substituted cyclohexane-1,2-diamine derivatives and related compounds as antimicrobial agents. IN 2008DE01462 A 20120914 (2012).
  6. Diwan S. Rawat,* Nitin Kumar, Mukul Sharma, Symmetrically and asymmetrically substituted tetraoxane compounds, methods of preparation and uses thereof. IN 2008DE02103 A 20100423 (2010).  
  7. Jeffrey M. Zaleski; Diwan Singh Rawat, Enediyne compounds and methods related thereto. US Patent No:  US 7,211,603 B1 (2007).
  8. Jeffrey M. Zaleski; Diwan Singh Rawat, Compounds, compositions, and methods for photodynamic therapy. US Patent No:  US 6,828,439 B1 (2004).