priyamvada_singh

Dr. Priyamvada Singh (nee’ Poonam)

(Associate Professor)

Email
View Profile
Website

Priyamvada Singh, an alumna of the University of Delhi, completed her doctorate in 2012, with research focused on Synthetic Organic Chemistry. She began her academic career as an Assistant Professor (Ad-hoc) in the Department of Chemistry, University of Delhi, in January 2013. From July 2015 to January 2025, she served as a permanent faculty member at Miranda House, University of Delhi. In January 2025,she joined the Department of Chemistry at the University of Delhi as an Associate Professor.

Dr. Singh’s work spans medicinal chemistry and chemical biology, with a special focus on Drug Design and Discovery. Her research group focuses on developing innovative synthetic methodologies and designing and developing biologically important heterocyclic small molecules. Their work operates at the interface of chemistry, medicine, biology, and materials science, aiming to address challenges in therapeutic discovery. She is associated with well-renowned collaborators worldwide. Within these frameworks, she was honoured as a Visiting Assistant Professor, the University of Cyberjaya, Malaysia (2024), an Affiliate Assistant Professorship at the Department of Medicine, University of Loyola, Chicago, USA (2019-21), a CAPES Fellowat the Federal Rural University of Pernambuco-UFRPE in Recife, Brazil, in 2019 and an Adjunct-Visiting Senior Researcher at the South Ural State University, Russia (2018-20). She has been a recipient of the prestigious SERB International Research Experience (SIRE) Fellowship (2023) by SERB, IoE Fellow (2022) and ILLL Fellow (2021) by the University of Delhi, Distinguished Investigator Award at the International Conference, ICBTM-2019, UGC Travel Grant Award (2017) sponsored by Government of India.  Beyond research, Dr. Singh is a dedicated educator and mentor, deeply involved in curriculum development and committed to creating a collaborative, research-driven learning environment for students.

Selected Publications:

  1. Upadhyay, C.; Bhattacharya, S.; Kumar, S.; Vashist, K.; Zhang, X.; Gagnon, D.; Singh, P.; Zhan, P.; Richard, D.; Rathi, B.; Singh, A. P.; Singh, P.* Fluorinated piperazine hydroxyethylamine analogs as potential antiplasmodial candidates: Synthesis, biological assays and pharmacological studies. ChemMedChem, 2025, e202400616 
  2. Kumar, S.; Kumar, D.; Upadhyay, C.; Bansal, M.; Rathi, B.; Singh, P.* Functionalization of cellulose nanocrystals with bioactive scaffold: Synthesis, characterization, and biological studies. Int. J. Biol. Macromol. 2024, 282 (1), 136660
  3. Kumar, S.; Yadav, D.; Singh, D.; Shakya, K.; Rathi, B.; Poonam*, Recent developments on Junin virus, a causative agent for Argentine Hemorrhagic Fever. Rev. Med. Virol. 2023, e2419
  4. Kumar, S.; Sharma, N.; Dantas, W.; Nascimento, J. C. F. do; Maus, H.; Oliveira, R.; Pandit, U.; Singh, A. P.; Schirmeister, T.; Hazari, P.; Pena, L.; Poonam*; Rathi, B. A potent candidate against Zika virus infection: Synthesis, bioactivity, radiolabelling and biodistribution studies. New J. Chem. 2022, 46, 18764-18775
  5. Kumar, S.; Kovalenko, S.; Bhardwaj, S.; Sethi, A.; Gorobets N. Y.; Poonam*; Rathi B., Drug Repurposing against SARS-CoV-2 forecasted by computational approaches. Drug Discov. Today 2022, 27 (5), 2015-2027
  6. Upadhyay, C.; Sharma, N.; Kumar, S.; Sharma, P. P.; Fontinha, D.; Chhikara, B. S.; Mukherjee, B.; Kumar, D.; Prudencio, M.; Singh, A. P.; Poonam* Synthesis of new analogs of morpholine and their antiplasmodial evaluation against human malaria parasite Plasmodium falciparum. New J. Chem. 2022, 46, 250-262.
  7. Kumar, S.; Gupta Y.; Zak, S. E.; Upadhyay, C.; Sharma, N.; Herbert, A. S.; Durvasula, R.; Dye, J. M.; Poonam*; Kempaiah, P.; Rathi B., A novel compound active against SARS-CoV-2 targeting Uridylate-specific endoribonuclease (NendoU/NSP15): in silico and in vitro investigations. RSC Med. Chem. 2021, 12, 1757-1764.
  8. Kumar, S.; Sharma, P. P.; Upadhyay, C.; Kempaiah, P.; Rathi B.; Poonam* Multi-targeting approach for nsp3, nsp9, nsp12 and nsp15 protein targets of SARS-CoV-2 by Diosmin as illustrated by Molecular Docking and MD simulation methodologies. Methods 2021,195, 44-56
  9. Kumar, S.; Upadhyay, C.; Bansal, M.; Grishina, M.; Chhikara, B. S.; Potemkin, V.; Rathi, B.; Poonam*, Experimental and Computational Studies of Microwave-Assisted, Facile Ring Opening of Epoxide with Less Reactive Aromatic Amines in Nitromethane. ACS Omega 2020, 5 (30), 18746-18757 
  10. Kumar, S.; Sharma, P. P.; Shankar, U.; Kumar, D.; Joshi, S. K.; Pena, L.; Durvasula, R.; Kumar, A.; Kempaiah, P.; Poonam*; Rathi, B., Discovery of New Hydroxyethylamine Analogs against 3CLpro Protein Target of SARS-CoV-2: Molecular Docking, Molecular Dynamics Simulation, and Structure–Activity Relationship Studies. J. Chem. Inf. Model. 2020, 60 (12), 5754-5770.

Patents

  • Brijesh Rathi Prakasha Kempaiah, Agam P. Singh, Snigdha Singh, Yash Gupta, Neha Sharma, Poonam, Ravi Durvasula. Title of Invention: Hydroxyethyl amine based piperazine compounds and methods of producing and using the same for treating disease. CALXININ; US patent No. US 11,485,714 B2; Date of patent: 1 Nov. 2022 Granted